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[抗菌化疗的过敏副作用及其诊断方法]

[Allergic side-effects of antimicrobial chemotherapy and possibilities in their diagnosis].

作者信息

Stiller D, Zucker G

出版信息

Z Gesamte Inn Med. 1977 Aug 15;32(16):suppl 249-50.

PMID:595690
Abstract

In antimicrobial chemotherapy the allergic reactions are in the first place of the side-effects appearing. The most frequent cause of the iatrogenic contact eczema antimycotics and chloramphenicol are to be taken into consideration. Penicillin and its derivations and chloramphenicol form the main proportion of the allergic in systematic administration. The serologico-nephelometric two-step-method and the lymphocyte transformation test are useful methods for the diagnostics of drug allergies. In a use adequate to indication they are valuable adjuvants in the hand of the clinician.

摘要

在抗微生物化疗中,过敏反应是首先出现的副作用。应考虑医源性接触性湿疹最常见的原因是抗真菌药和氯霉素。青霉素及其衍生物和氯霉素在全身给药的过敏反应中占主要比例。血清学比浊两步法和淋巴细胞转化试验是诊断药物过敏的有用方法。在适当的适应症使用中,它们是临床医生手中有价值的辅助手段。

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