[尿酸在草酸钙肾结石中的意义]

[The significance of uric acid in calcium oxalate nephrolithiasis].

作者信息

Hartung R

出版信息

MMW Munch Med Wochenschr. 1975 Mar 7;117(10):387-90.

Abstract

The findings of serum diagnosis (urea nitrogen, creatinine, uric acid, calcium, phosphorus) in 247 patients with oxalate stone were divided according to sex, and the excretion of uric acid, calcium and phosphorus was estimated. Compared with the control group, the levels of serum uric acid and serum calcium were statistically significantly raised, the mean level not exceeding the normal range. The serum uric acid level was 25% above the normal range in men and 20% above in women, and in the upper range of normal in one third of each, men and women. The excretion of uric acid in women exceeds the normal level in 32% of cases and in 40% of the men, sometimes considerably. The connection between pathological uric acid levels in the serum and urine and the development of oxalate stone, as well as the therapeutic consequences are discussed.

摘要

对247例草酸盐结石患者的血清诊断结果（尿素氮、肌酐、尿酸、钙、磷）按性别进行了划分，并对尿酸、钙和磷的排泄情况进行了评估。与对照组相比，血清尿酸和血清钙水平在统计学上显著升高，平均水平未超过正常范围。男性血清尿酸水平高于正常范围25%，女性高于20%，男性和女性各有三分之一处于正常范围上限。女性尿酸排泄量超过正常水平的病例占32%，男性占40%，有时超出幅度较大。文中讨论了血清和尿液中病理性尿酸水平与草酸盐结石形成之间的关联以及治疗后果。