Petit C
Nephrologie. 1984;5(5):192-4.
Usually calcium nephrolithiasis is due to "idiopathic" hypercalciuria associated with failure of the compensatory mechanisms (dissolving substances and crystallisation inhibitors. Classically a sufficient diuresis, a low calcium diet, the phosphate ion or (and) the thiazidic diuretics manage to reduce the hypercalciuria and to decrease the chances of relapse. This aim may be differently reached when hyperuricosuria is associated with hypercalciuria. The use of uric acid synthesis inhibitors (allopurinol, thiopurinol) brings the frequency of the recurring stone formation down and... the calciuria often. Series dealing with 141 calcium lithiasis with hyperuricosuria.
通常，钙结石病是由于“特发性”高钙尿症以及代偿机制（溶解物质和结晶抑制剂）失效所致。传统上，充足的利尿、低钙饮食、磷酸根离子或（和）噻嗪类利尿剂可降低高钙尿症，并减少复发几率。当高尿酸尿症与高钙尿症并存时，实现这一目标的方式可能有所不同。使用尿酸合成抑制剂（别嘌呤醇、硫嘌呤醇）可降低复发性结石形成的频率，而且……常常降低尿钙水平。对141例伴有高尿酸尿症的钙结石病病例进行了系列研究。
