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[结节病预后的临床与尸检研究]

[Clinical and autopsy studies on prognosis of sarcoidosis].

作者信息

Sugie T, Hashimoto N, Iwai K

机构信息

Division of Pulmonary Disease, Fukujyuji Hospital, Japan Anti-Tuberculosis Association.

出版信息

Nihon Rinsho. 1994 Jun;52(6):1567-70.

PMID:8046842
Abstract

Prognosis of 435 sarcoidosis patients and epidemiologic features were studied in 320 autopsy cases. About 80-90% of Stage I or II patients showed spontaneous remission. The prognosis of Stage III patient was poor and corticosteroid therapy seemed to be rather ineffective. The proportion of sarcoidosis autopsy, relative to total autopsy cases, appears to be increasing. The number of female cases was about 2 times larger than that of males. Only 43.4% of the total autopsy cases had been diagnosed clinical sarcoidosis. Over 5 times more sarcoidosis patients than clinically diagnosed were estimated to exist. Approximately one half of the sarcoidosis autopsy cases were related to cardiac sarcoidosis.

摘要

对320例尸检病例中的435例结节病患者的预后及流行病学特征进行了研究。约80 - 90%的Ⅰ期或Ⅱ期患者出现自发缓解。Ⅲ期患者预后较差,糖皮质激素治疗似乎效果不佳。结节病尸检病例占总尸检病例的比例似乎在增加。女性病例数约为男性的2倍。在全部尸检病例中,仅43.4%临床诊断为结节病。据估计,实际存在的结节病患者数量比临床诊断出的多5倍以上。约一半的结节病尸检病例与心脏结节病有关。

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