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对照对应激性胃糜烂的影响:采用主动穿梭箱回避学习并设置配对对照。

The effects of control on stress-induced gastric erosions: the use of active shuttle-box avoidance learning with yoked controls.

作者信息

Böhmelt A H, Winneke G, Boucsein W

机构信息

Division of Physiological Psychology, University of Wuppertal, Germany.

出版信息

Physiol Behav. 1994 Jun;55(6):1101-8. doi: 10.1016/0031-9384(94)90393-x.

DOI:10.1016/0031-9384(94)90393-x
PMID:8047577
Abstract

The aim of the present study was to investigate effects of instrumental control on the development of stress-induced gastric erosions by using a shuttle-box paradigm with yoked controls. In Experiment 1 the learning conditions had a reinforcement ratio of only 70% to increase stress during the short-term learning session. No significant differences of the mean cumulative length of gastric erosions between active avoiding and yoked groups were found. Experiment 2 tested three different reinforcement conditions (70%, 90%, 100%) with yoked groups. Again, no significant differences of the mean cumulative length of erosions between active avoiding and yoked control groups were obtained. Instead, the length of erosions decreased with increasing reinforcement. Taken together, the data show that the frequency of unavoided noxious stimuli as a function of the reinforcement schedule can be seen as a major influence on the development of gastric erosions in a shuttle-box paradigm.

摘要

本研究的目的是通过使用带有配对对照组的穿梭箱范式,探讨工具性控制对应激性胃糜烂发展的影响。在实验1中,学习条件的强化率仅为70%,以在短期学习过程中增加应激。主动回避组和配对组之间胃糜烂的平均累积长度没有显著差异。实验2对配对组测试了三种不同的强化条件(70%、90%、100%)。同样,主动回避组和配对对照组之间糜烂的平均累积长度没有显著差异。相反,糜烂的长度随着强化率的增加而减少。综上所述,数据表明,在穿梭箱范式中,作为强化时间表函数的不可避免的有害刺激频率可被视为对胃糜烂发展的主要影响因素。

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