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[分枝杆菌个体代表的蛋白质光谱特征]

[Characteristics of the protein spectra of individual representatives of mycobacteria].

作者信息

Dykhno M M, Fadeeva N I, Pershin G N, Sarycheva I M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1975 Jan(1):108-13.

PMID:804775
Abstract

A study of proteinograms of some strains of mycobacteria with the use of the method of electrophoresis in polyacrylamide gel showed that individual strains had characteristic protein spectra which could serve as one of the possible taxonomic characteristics. Analysis of proteinograms of three groups of mycobacteria (tuberculosis, atypical and saprophytes) by electrophoretic mobility of the fractions, with consideration to their homologous character and by the intensity of protein fractions in the mobility zones pointed to heterogeneity of the group of atypical strains and their greater similarity to tuberculosis mycobacteria than to acid-fast saprophytes. Proteinograms of strains H37 Rv and Bov-8 proved to be identical; a marked similarity between the protein spectra of M. avium and M. battey was revealed.

摘要

一项使用聚丙烯酰胺凝胶电泳法对某些分枝杆菌菌株蛋白质图谱的研究表明,个别菌株具有特征性的蛋白质谱,可作为可能的分类特征之一。通过各组分的电泳迁移率对三组分枝杆菌(结核分枝杆菌、非典型分枝杆菌和腐生菌)的蛋白质图谱进行分析,考虑到它们的同源性以及迁移区中蛋白质组分的强度,结果表明非典型菌株组具有异质性,且它们与结核分枝杆菌的相似性高于抗酸腐生菌。菌株H37 Rv和Bov-8的蛋白质图谱被证明是相同的;还揭示了鸟分枝杆菌和巴氏分枝杆菌蛋白质谱之间存在明显的相似性。

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