Sunheimer R L, Finck C, Mortazavi S, McMahon C, Pincus M R
Department of Pathology, SUNY Health Science Center, Syracuse 13210.
Ann Clin Lab Sci. 1994 May-Jun;24(3):239-42.
A 79-year-old native American female with a history of diabetes mellitus, but no history of hepatic or renal disease, presented with anasarca and hypoalbuminemia. Laboratory tests for fecal alpha 1-antitrypsin and an indium III-labeled plasma transferrin nuclear scan revealed a protein-losing enteropathy. A serological test was positive for antinuclear antibody in a titer of 1:1250 with a homogeneous pattern. This finding combined with low normal serum complement levels suggested the diagnosis of systemic lupus erythematosus (SLE). This case is unusual in that protein-losing enteropathy was the only presenting symptoms. The late onset of this disease is also unusual.
一名79岁的美国原住民女性，有糖尿病史，但无肝脏或肾脏疾病史，出现全身水肿和低白蛋白血症。粪便α1-抗胰蛋白酶检测及铟III标记的血浆转铁蛋白核素扫描显示为蛋白丢失性肠病。血清学检测抗核抗体阳性，滴度为1:1250，呈均质型。这一发现结合血清补体水平略低提示系统性红斑狼疮（SLE）的诊断。该病例不同寻常之处在于蛋白丢失性肠病是唯一的首发症状。这种疾病的迟发性也不常见。
