与系统性红斑狼疮相关的蛋白丢失性肠病：对环磷酰胺的反应
Protein-losing enteropathy associated with systemic lupus erythematosus: response to cyclophosphamide.
作者信息
Werner de Castro Gláucio R, Appenzeller Simone, Bértolo Manoel B, Costallat Lílian Tereza Lavras
机构信息
Rheumatology Unit, Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
出版信息
Rheumatol Int. 2005 Mar;25(2):135-8. doi: 10.1007/s00296-004-0483-8. Epub 2004 Jul 13.
Protein-losing enteropathy is a rare manifestation of systemic lupus erythematosus (SLE) leading to hypoalbuminemia and anasarca. We report the case of a woman with SLE who presented chronic hypoalbuminemia diagnosed as protein-losing enteropathy associated with SLE. She was refractory to prednisone and azathioprine administration but showed good response to cyclophosphamide. The diagnosis and management of hypoalbuminemia in lupus-associated enteropathy are discussed.
蛋白丢失性肠病是系统性红斑狼疮（SLE）的一种罕见表现，可导致低白蛋白血症和全身水肿。我们报告了一例患有SLE的女性病例，该患者出现慢性低白蛋白血症，诊断为与SLE相关的蛋白丢失性肠病。她对泼尼松和硫唑嘌呤治疗无效，但对环磷酰胺反应良好。本文讨论了狼疮相关性肠病中低白蛋白血症的诊断和管理。
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