儿科肿瘤学中的每日一次抗生素治疗方案。
Once daily antibiotic regimen in paediatric oncology.
作者信息
Bouffet E, Fuhrmann C, Frappaz D, Couillioud D, Artiges V, Charra C, Bouhour D, Brunat Mentigny M
机构信息
Paediatric Department, Centre L. Bérard, Lyon, France.
出版信息
Arch Dis Child. 1994 Jun;70(6):484-7. doi: 10.1136/adc.70.6.484.
Abstract
The feasibility and efficacy of a once daily antibiotic regimen were assessed in children with malignant tumours. Over a 44 month period, 296 febrile episodes were treated with a regimen of once daily ceftriaxone-amikacin (and teicoplanin or vancomycin if the patient had a central line). The treatment was successful in 272 (92%) episodes without modification of the antibiotic regimen, and only one patient died of uncontrolled sepsis. A once daily antibiotic regimen is therefore feasible and worthwhile in the treatment of febrile episodes in children with cancer.
摘要
对患有恶性肿瘤的儿童采用每日一次抗生素疗法的可行性和疗效进行了评估。在44个月的时间里，296次发热发作采用每日一次头孢曲松 - 阿米卡星疗法进行治疗（如果患者有中心静脉导管，则加用替考拉宁或万古霉素）。272次发作（92%）治疗成功，无需调整抗生素疗法，只有一名患者死于无法控制的败血症。因此，每日一次抗生素疗法在治疗癌症患儿的发热发作方面是可行且值得的。
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本文引用的文献
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