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脂质体两性霉素B治疗肝念珠菌病

Liposomal amphotericin B in hepatic candidosis.

作者信息

Sharland M, Hay R J, Davies E G

机构信息

Department of Child Health, St George's Hospital Medical School, London.

出版信息

Arch Dis Child. 1994 Jun;70(6):546-7. doi: 10.1136/adc.70.6.546.

Abstract

A 4 year old girl treated with a standard chemotherapy protocol for acute lymphoblastic leukaemia developed hepatic candidosis during the consolidation phase. This relapsed after a prolonged course of amphotericin B and flucytosine. An eight week course of liposomal amphotericin produced a marked clinical improvement which was sustained for one year. A subsequent relapse was associated with transformation to myelodysplastic leukaemia.

摘要

一名4岁女童接受急性淋巴细胞白血病标准化疗方案治疗,在巩固期发生肝念珠菌病。在接受两性霉素B和氟胞嘧啶的长期治疗后病情复发。为期八周的脂质体两性霉素治疗带来了显著的临床改善,且持续了一年。随后的复发与转化为骨髓增生异常白血病有关。

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