Wakabayashi I, Yoshimoto S, Masui H, Sakamoto K, Nishina M, Shimizu M, Nakamura T
Department of Hygiene, Hyogo College of Medicine.
Nihon Koshu Eisei Zasshi. 1994 May;41(5):441-51.
Students, 60 females (mean age of 19 years) and 54 male (mean age of 23.8 years), were studied for relationships between serum vitamin A concentration (V-A level) and subjective health (by CMI method), birth order, blood and urinary parameters, dietary intake and food preferences. V-A level for females was significantly lower than for males. V-A level significantly and positively correlated to the parameters of hepatic enzymes (gamma-GTP, GOT, GPT), lipid (T-chol, TG) and urinary Na/K. The V-A level showed independent significant correlation to gamma-GTP in multiple regression analysis. V-A level of those born second in birth order showed a tendency to be lower than those first and third in birth order. In females, subjects without subjective CMI complaints had higher level of V-A than those with complaints. This tendency was not seen in males except for items related to the respiratory system. V-A level showed an apparent increase corresponding to daily intake of soybean and vegetables in females, and with amounts of drinking or smoking in male. In males, V-A levels showed a significant positive correlation to serum oxygen peroxide measured by malondialdehyde and did not show an anti-peroxidation effect. In addition positive correlation to total cholesterol was observed in males.
对60名女性(平均年龄19岁)和54名男性(平均年龄23.8岁)学生进行了研究,以探讨血清维生素A浓度(V-A水平)与主观健康状况(采用CMI方法)、出生顺序、血液和尿液参数、饮食摄入量及食物偏好之间的关系。女性的V-A水平显著低于男性。V-A水平与肝酶(γ-GTP、GOT、GPT)、脂质(总胆固醇、甘油三酯)及尿钠/钾参数呈显著正相关。在多元回归分析中,V-A水平与γ-GTP呈独立显著相关。出生顺序为第二的人的V-A水平有低于出生顺序为第一和第三的人的趋势。在女性中,无CMI主观不适主诉的受试者的V-A水平高于有主诉的受试者。除与呼吸系统相关的项目外,男性未出现这种趋势。女性的V-A水平随大豆和蔬菜日摄入量的增加而明显升高,男性则随饮酒量或吸烟量的增加而升高。在男性中,V-A水平与通过丙二醛测定的血清过氧化氢呈显著正相关,且未表现出抗氧化作用。此外,在男性中观察到与总胆固醇呈正相关。