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灵长类动物玻璃体内注射自体血。

Intravitreal injection of autologous blood in primates.

作者信息

Bennett T O, Peyman G A, Vlchek J K

出版信息

Can J Ophthalmol. 1975 Apr;10(2):248-54.

PMID:804982
Abstract

Thirteen owl monkeys received intravitreal injections of 0.3 ml of autologous blood in single or multiple injections. Blood was antiocoagulated either with heparin to inhabit clot formation or with citrate to allow clot production within the vitreous body. Clinical observations showed that approximately 60% of the heparinized eyes cleared, whereas only about 5% of the citrated eyes did. Thus, clotting appears to have a significant effect on the clearance of blood from the vitreous chamber. In addition to the abscence of hemosiderosis, histological and ultrastructural studies of retinas showed no retinal damage.

摘要

13只夜猴接受了玻璃体内注射,单次或多次注射0.3毫升自体血。血液用肝素抗凝以抑制凝血形成,或用柠檬酸盐抗凝以使玻璃体体内形成凝血。临床观察表明,约60%使用肝素的眼睛血液清除,而使用柠檬酸盐的眼睛只有约5%清除。因此,凝血似乎对玻璃体腔血液清除有显著影响。除了没有血铁沉着症外,视网膜的组织学和超微结构研究未显示视网膜损伤。

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