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补充二氧化碳治疗难治性睡眠呼吸暂停

Treatment of refractory sleep apnea with supplemental carbon dioxide.

作者信息

Badr M S, Grossman J E, Weber S A

机构信息

Department of Medicine, University of Wisconsin Hospital and Clinics, Madison.

出版信息

Am J Respir Crit Care Med. 1994 Aug;150(2):561-4. doi: 10.1164/ajrccm.150.2.8049848.

DOI:10.1164/ajrccm.150.2.8049848
PMID:8049848
Abstract

Sleep apnea syndrome is a relatively common disorder characterized by periodic cessation of breathing during sleep because of upper airway obstruction (obstructive sleep apnea) or by reduction of ventilatory drive (central sleep apnea). We report the case of a middle-aged, obese man who underwent tracheostomy for the treatment of obstructive sleep apnea documented by polysomnography. Although tracheostomy resulted in marked clinical improvement, relief of upper airway obstruction unmasked severe central sleep apnea. We report the successful treatment of this patient's central sleep apnea syndrome with the use of supplemental CO2 therapy.

摘要

睡眠呼吸暂停综合征是一种相对常见的病症,其特征为睡眠期间因上气道阻塞(阻塞性睡眠呼吸暂停)导致呼吸周期性停止,或因通气驱动力降低(中枢性睡眠呼吸暂停)而出现呼吸周期性停止。我们报告一例中年肥胖男性病例,该患者因阻塞性睡眠呼吸暂停接受了气管切开术,多导睡眠图记录证实了这一情况。尽管气管切开术使临床症状有显著改善,但上气道阻塞的缓解却暴露出严重的中枢性睡眠呼吸暂停。我们报告了使用补充二氧化碳疗法成功治疗该患者中枢性睡眠呼吸暂停综合征的情况。

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