Murro A M, Park Y D, King D W, Gallagher B B, Smith J R, Littleton W
Department of Neurology, VA Medical Center, Augusta, GA 30912.
J Clin Neurophysiol. 1994 Mar;11(2):216-9. doi: 10.1097/00004691-199403000-00006.
We determined the accuracy and sensitivity of scalp-sphenoidal EEG for seizure focus localization in 50 patients who became seizure-free or had rare seizures following temporal lobectomy. EEG localization was based on concordant interpretations of scalp-sphenoidal ictal EEG by three independent interpreters. All patients became seizure-free or had rare seizures following temporal lobectomy. Localization from EEG disagreed with the side of surgery in only 1 (2%) of 50 patients. We identified 3 distinct patient groups with a low, moderate, and high likelihood of having a focal ictal EEG pattern during a seizure. These groups comprised 31% (low likelihood), 44% (moderate likelihood), and 25% (high likelihood) of patients. A model based on these results suggests that with multiple ictal EEG recordings, accurate localization from scalp-sphenoidal EEG is possible in approximately up to 65-70% of patients with temporal lobe epilepsy.
我们测定了50例在颞叶切除术后癫痫发作停止或很少发作的患者中，头皮-蝶骨电极脑电图对癫痫发作灶定位的准确性和敏感性。脑电图定位基于三位独立解读人员对头皮-蝶骨发作期脑电图的一致解读。所有患者在颞叶切除术后癫痫发作停止或很少发作。脑电图定位与手术侧不符的情况仅在50例患者中的1例（2%）出现。我们识别出3个不同的患者组，其在癫痫发作时出现局灶性发作期脑电图模式的可能性低、中、高。这些组分别占患者的31%（低可能性）、44%（中等可能性）和25%（高可能性）。基于这些结果的一个模型表明，通过多次发作期脑电图记录，在大约65% - 70%的颞叶癫痫患者中，从头皮-蝶骨电极脑电图进行准确的定位是可能的。
