Murro A M, Park Y D, King D W, Gallagher B B, Smith J R, Yaghmai F, Toro V, Figueroa R E, Loring D W, Littleton W
Department of Neurology, VA Medical Center, Augusta, GA.
Neurology. 1993 Dec;43(12):2531-3. doi: 10.1212/wnl.43.12.2531.
We determined the accuracy of volumetric MRI (based on identification of unilateral hippocampal atrophy) and scalp-sphenoidal EEG (based on concordant interpretations of scalp-sphenoidal ictal EEG by three independent interpreters) for seizure focus localization in 20 patients with temporal lobe epilepsy. All patients became seizure-free or had rare seizures following temporal lobectomy. Among the 20 patients, nine (45%) met both MRI and EEG localization criteria, six (30%) met MRI localization criteria alone, three (15%) met EEG localization criteria alone, and two patients (10%) did not meet either localization criteria. In the 18 patients meeting MRI or EEG localization criteria, the predicted localization agreed with the side of temporal lobectomy. These results suggest that a noninvasive approach combining MRI and EEG will correctly localize the side of seizure onset in most patients with temporal lobe epilepsy.
我们确定了容积性磁共振成像（基于单侧海马萎缩的识别）和头皮-蝶骨电极脑电图（基于三名独立解读员对头皮-蝶骨发作期脑电图的一致解读）在20例颞叶癫痫患者中对癫痫发作灶定位的准确性。所有患者在颞叶切除术后均无癫痫发作或仅有罕见发作。在这20例患者中，9例（45%）同时符合磁共振成像和脑电图定位标准，6例（30%）仅符合磁共振成像定位标准，3例（15%）仅符合脑电图定位标准，2例（10%）不符合任何定位标准。在18例符合磁共振成像或脑电图定位标准的患者中，预测的定位与颞叶切除术的一侧相符。这些结果表明，结合磁共振成像和脑电图的非侵入性方法将在大多数颞叶癫痫患者中正确定位癫痫发作起始的一侧。
