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B群和C群脑膜炎奈瑟菌共有的血清型抗原的流行病学研究。

Epidemiologic studies of serotype antigens common to groups B and C Neisseria meningitidis.

作者信息

Munford R S, Patton C M, Gorman G W

出版信息

J Infect Dis. 1975 Mar;131(3):286-90. doi: 10.1093/infdis/131.3.286.

DOI:10.1093/infdis/131.3.286
PMID:805184
Abstract

Antisera to strains of group B Neisseria meningitidis (Frash) were used to serotype strains of group C N. meningitidis by an agar gel double diffusion technique. Serotupe antigen(s) were found in most strains examined, and the presence of group B serotype 2 antigen was associated with associated with sulfonamide resistance in group C strains isolated from sporadic cases and from cases and carriers in military and civilian epidemics of disease caused by sulfonamide-resistant group C organisms. Serotyping by the agar diffusion test apperars to be a useful tool for epidemiologic studies of disease caused by groups B and C N. meningitidis.

摘要

用针对B群脑膜炎奈瑟菌(弗拉施株)的抗血清,通过琼脂凝胶双向扩散技术对C群脑膜炎奈瑟菌菌株进行血清分型。在所检测的大多数菌株中发现了血清型抗原,并且在从散发病例以及由耐磺胺C群菌株引起的军队和平民疾病流行中的病例及携带者分离出的C群菌株中,B群2型血清型抗原的存在与磺胺耐药性相关。琼脂扩散试验血清分型似乎是对由B群和C群脑膜炎奈瑟菌引起的疾病进行流行病学研究的一种有用工具。

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Epidemiologic studies of serotype antigens common to groups B and C Neisseria meningitidis.B群和C群脑膜炎奈瑟菌共有的血清型抗原的流行病学研究。
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