Fleming C R, Newcomer A D, Stephens D H, Carlson H C
Mayo Clin Proc. 1975 May;50(5):244-8.
Diverticula rarely occur within the lumen of the duodenum. They arise near the papilla of Vater and extend distally. The diverticulum is lined on both sides with duodenal mucosa, and its eccentric opening is usually proximal in the sac. The diverticulum results from incomplete recanalization of the intestinal lumen after the proliferative epithelial stage in the 7-week embryo and represents either a remnant of one of two channels formed during recanalization or a distal ballooning of a congenital duodenal diaphragm. Although the patient with a diverticulum may be asymptomatic, most patients present with abdominal pain and obstructive symptoms; pancreatitis and gastrointestinal bleeding may be associated with the diverticulum. Barium study shows a characteristic radiolucent halo that represents the wall of the diverticulum. Surgery should be approached with caution because injury to the papilla is a hazard, and in children, coexisting congenital anomalies may be present.
憩室很少出现在十二指肠腔内。它们在 Vater 乳头附近形成并向远端延伸。憩室两侧衬有十二指肠黏膜,其偏心开口通常位于囊袋近端。憩室是由于 7 周龄胚胎增殖上皮阶段后肠腔再通不完全所致,代表再通过程中形成的两个通道之一的残余部分,或先天性十二指肠隔膜的远端扩张。虽然憩室患者可能无症状,但大多数患者表现为腹痛和梗阻症状;胰腺炎和胃肠道出血可能与憩室有关。钡剂造影显示特征性的透光晕,代表憩室壁。手术应谨慎进行,因为损伤乳头有风险,且在儿童中可能存在并存的先天性异常。