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Viral interactions with the host-cell cytoskeleton: the role of retroviral proteases.

作者信息

Luftig R B, Lupo L D

机构信息

Dept of Microbiology, Immunology and Parasitology, Louisiana State University Medical Center, New Orleans 70112-1393.

出版信息

Trends Microbiol. 1994 May;2(5):178-82. doi: 10.1016/0966-842x(94)90669-6.

Abstract

A surprisingly large number of animal viruses interact with cytoskeletal elements inside infected cells at different stages of replication. For example, a viral protease is activated during assembly of murine leukemia viruses at the cell surface, which causes both the morphological conversion of 'immature' to 'mature' particles and a drastic reduction of the actin stress fiber network.

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