Stenager E, Knudsen L, Jensen K
Clinical Neuro-Psychiatric Research Unit, Odense University Hospital, Denmark.
Ital J Neurol Sci. 1994 Mar;15(2):97-101. doi: 10.1007/BF02340120.
The aim of the study was to examine the correlation between anxiety and physical impairment and to discover whether anxiety correlated with specific forms of cognitive dysfunction. Ninety-four patients (42 females, 52 males) with definite MS entered the study. Anxiety was measured using the State-Trait Anxiety Inventory, physical impairment by means of the Kurtzke Disability Status scale, and cognitive impairment by using the Trail Making, Symbol Digit Modalities, Auditory Verbal Learning, Story Recall and the Recurring Figures tests. Moderately handicapped patients (DSS 4-5) showed signs of anxiety, and physical impairment correlated with anxiety (p < 0.05; d.f. 1.92). Trail Making also correlated with anxiety (p < 0.01; d.f. 1.86). On the basis of the results of this and previous studies, it is concluded that anxiety can be a sign of cognitive dysfunction, physical impairment or social strain.
该研究的目的是检验焦虑与身体损伤之间的相关性，并探究焦虑是否与特定形式的认知功能障碍相关。94例确诊为多发性硬化症的患者（42名女性，52名男性）参与了该研究。使用状态-特质焦虑量表测量焦虑程度，通过库尔茨克残疾状态量表评估身体损伤情况，并运用连线测验、符号数字模式测验、听觉词语学习测验、故事回忆测验和重复图形测验来检测认知损伤。中度残疾患者（残疾状态量表评分为4-5分）表现出焦虑迹象，且身体损伤与焦虑相关（p < 0.05；自由度为1,92）。连线测验也与焦虑相关（p < 0.01；自由度为1,86）。基于本研究及先前研究的结果，得出结论：焦虑可能是认知功能障碍、身体损伤或社会压力的一种表现。
