Obata A, Yoshikawa J, Yoshida K, Akasaka T, Yamaura Y, Shakudo M, Takagi T, Miyake S, Shomura T, Okada Y
Department of Cardiology, Kobe General Hospital.
J Cardiol. 1994 Jul-Aug;24(4):311-6.
Patients developing residual or recurrent mitral regurgitation (MR) increased to moderate or severe grade after mitral valve reconstruction for MR were investigated by correlating the lesion and operation method with the echocardiographic course of postoperative MR. Postoperative moderate or severe grade MR [more than 4.0 cm2 color Doppler flow area on postoperative transesophageal echocardiography (TEE)] occurred in 21 of 80 mitral valve reconstruction patients. If residual MR caused more than 2.0 cm2 color Doppler flow area on intraoperative TEE, the MR increased to moderate or severe grade during the follow-up period. Postoperative moderate or severe MR occurred more frequently in lesions of the anterior mitral leaflet than the posterior mitral leaflet (45.8% vs 6.5%, p < 0.001), and in elongated chordae than in torn chordae (52.9% vs 14.3%, p < 0.005). Chordal shortening for elongated chordae could correct MR at operation but MR recurred and increased gradually to moderate or severe grade in half of these cases. Chordal reconstruction with polytetrafluorethylene suture is expected to achieve better results than chordal shortening. The causes of postoperative MR could usually be identified by comparative investigation of echocardiographic course, lesion, and operation method. Postoperative moderate or severe MR occurs more often in lesions of the anterior mitral leaflet or cases of elongated chordae. Residual MR should be suppressed to less than 2.0 cm2 color Doppler flow area on intraoperative TEE.
对二尖瓣反流(MR)行二尖瓣重建术后出现残余或复发性MR且加重至中度或重度的患者,通过将病变及手术方法与术后MR的超声心动图病程相关联进行研究。80例二尖瓣重建患者中,21例术后出现中度或重度MR[术后经食管超声心动图(TEE)彩色多普勒血流面积超过4.0 cm²]。若术中TEE显示残余MR的彩色多普勒血流面积超过2.0 cm²,则随访期间MR会加重至中度或重度。术后中度或重度MR在前叶病变患者中比后叶病变患者更常见(45.8%对6.5%,p<0.001),在腱索延长患者中比腱索断裂患者更常见(52.9%对14.3%,p<0.005)。对腱索延长进行腱索缩短术可在术中纠正MR,但其中半数病例MR会复发并逐渐加重至中度或重度。预计用聚四氟乙烯缝线进行腱索重建比腱索缩短术效果更好。术后MR的原因通常可通过对超声心动图病程、病变及手术方法的对比研究来确定。术后中度或重度MR在前叶病变或腱索延长病例中更常见。术中TEE应将残余MR的彩色多普勒血流面积控制在2.0 cm²以下。