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黑腹果蝇X染色体基部热诱导重组的差异敏感性及其靶点

Differential sensitivities and the target of heat-induced recombination at the base of the X chromosome of Drosophila melanogaster.

作者信息

Lifschytz E

出版信息

Genetics. 1975 Feb;79(2):283-94. doi: 10.1093/genetics/79.2.283.

DOI:10.1093/genetics/79.2.283
PMID:805749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213272/
Abstract

The effect of heat on two small adjacent segments at the base of the X chromosome was examined. Recombination in the two segments delimited by recessive lethals was measured after treatment with 30 degree and 34 degree. Both segments were sensitive at 30 degree, while only the proximal one responded to 34 degree treatment. When the same segments were studied in structural heterozygotes (for deletions) the relative increase in recombination was greater, suggesting that heat exerts its effect on the "pairing" rather than the "exchange" components of crossing over. The effect of c (3) G/+ on the same segments in both homozygous and heterozygous structurals was studied. The results indicate that this meiotic mutant mediates its effect on a step different than that affected by heat.

摘要

研究了热对X染色体基部两个相邻小片段的影响。在用30摄氏度和34摄氏度处理后,测量了由隐性致死基因界定的两个片段中的重组情况。两个片段在30摄氏度时都敏感,而只有近端片段对34摄氏度处理有反应。当在结构杂合子(缺失)中研究相同片段时,重组的相对增加更大,这表明热对交换的“配对”而非“交换”成分产生影响。研究了c(3)G/+在纯合和杂合结构中对相同片段的影响。结果表明,这种减数分裂突变体在一个不同于热影响的步骤上介导其作用。

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1
Differential sensitivities and the target of heat-induced recombination at the base of the X chromosome of Drosophila melanogaster.黑腹果蝇X染色体基部热诱导重组的差异敏感性及其靶点
Genetics. 1975 Feb;79(2):283-94. doi: 10.1093/genetics/79.2.283.
2
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引用本文的文献

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Genetics. 2003 Apr;163(4):1337-56. doi: 10.1093/genetics/163.4.1337.
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Molecular and cytogenetic analysis of the heterochromatin-euchromatin junction region of the Drosophila melanogaster X chromosome using cloned DNA sequences.利用克隆的DNA序列对黑腹果蝇X染色体异染色质-常染色质交界区域进行分子和细胞遗传学分析。
Genetics. 1990 Aug;125(4):821-32. doi: 10.1093/genetics/125.4.821.

本文引用的文献

1
An Effect of Temperature and Age on Crossing-Over in the First Chromosome of Drosophila Melanogaster.温度和年龄对黑腹果蝇第一染色体交换的影响
Proc Natl Acad Sci U S A. 1926 Aug;12(8):530-2. doi: 10.1073/pnas.12.8.530.
2
Interchromosomal effects on crossing over in Drosophila.果蝇中染色体间对交换的影响。
Cold Spring Harb Symp Quant Biol. 1951;16:175-97. doi: 10.1101/sqb.1951.016.01.015.
3
The effect of x-rays on female germ cells of Drosophila melanogaster. 3. A comparison with heat-treatment on crossing-over in the X-chromosome.X射线对黑腹果蝇雌性生殖细胞的影响。3. 与X染色体交换中热处理的比较。
Mutat Res. 1968 Jan-Feb;5(1):93-107. doi: 10.1016/0027-5107(68)90083-3.
4
Evidence bearing on the coincidence of exchange and DNA replication in the oöcyte of Drosophila melanogaster.关于黑腹果蝇卵母细胞中交换与DNA复制同时发生的证据。
Proc Natl Acad Sci U S A. 1965 Jun;53(6):1340-6. doi: 10.1073/pnas.53.6.1340.
5
The localization of "ordinary" sex-linked genes in section 20 of the polytene X chromosome of Drosophila melanogaster.“普通”性连锁基因在黑腹果蝇多线X染色体第20节段中的定位。
Chromosoma. 1973 Nov 21;44(2):183-202. doi: 10.1007/BF00329116.