抑制宿主蛋白质合成的毒素。
Toxins that inhibit host protein synthesis.
作者信息
Obrig T G
机构信息
Department of Microbiology and Immunology, University of Rochester, School of Medicine and Dentistry, New York 14642.
出版信息
Methods Enzymol. 1994;235:647-56. doi: 10.1016/0076-6879(94)35178-3.
PMID:8057934
Abstract
Methods have been described that are sufficient to determine if a bacterial protein toxin is a selective inhibitor of eukaryotic protein synthesis, and, if so, which part of the overall process is affected. More defined assays are presented for studying the steps of peptide elongation as this is where such toxins have been shown to act.
摘要
已经描述了一些方法，这些方法足以确定一种细菌蛋白毒素是否是真核生物蛋白质合成的选择性抑制剂，如果是，那么整个过程的哪一部分会受到影响。本文还介绍了更明确的测定方法，用于研究肽链延伸步骤，因为已证明此类毒素作用于此。
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