Malik A S
Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan.
Med J Malaysia. 1994 Mar;49(1):12-6.
In view of controversial reports about the role of prelabour rupture of foetal membranes (PROM) in neonatal morbidity and to study the association of PROM with infections and meconium aspiration syndrome (MAS), a prospective case control study was conducted in a level II nursery of Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan. Of the 111 neonates with PROM studied, 18 developed clinical problems (septicaemia and other specific problems such as pneumonia, omphalitis, skin infection and MAS) while 5/56 of the control group developed similar problems. The difference between the two groups was not significant (p < 0.30). There was no neonatal death. It is concluded that PROM is not associated with neonatal morbidity. Neonates with this problem alone do not need to be admitted to the neonatal nursery.
鉴于关于胎膜早破（PROM）在新生儿发病中作用的报道存在争议，并且为了研究胎膜早破与感染及胎粪吸入综合征（MAS）之间的关联，在马来西亚理科大学医院哥打基纳巴卢分院二级新生儿重症监护室进行了一项前瞻性病例对照研究。在研究的111例胎膜早破新生儿中，18例出现临床问题（败血症及其他特定问题，如肺炎、脐炎、皮肤感染和胎粪吸入综合征），而对照组56例中有5例出现类似问题。两组之间的差异无统计学意义（p<0.30）。无新生儿死亡。结论是胎膜早破与新生儿发病无关。仅患有此问题的新生儿无需入住新生儿重症监护室。
