Zhang H P, Zhou S M
First Hospital, Beijing Medical University.
Zhonghua Fu Chan Ke Za Zhi. 1990 May;25(3):140-2, 187.
Maternal and neonatal white blood cell counts, neonatal pharyngeal culture, and histologic examination of placenta were done in 55 term pregnancies with premature rupture of fetal membranes (PROM) and in 52 term pregnancies without PROM to study the correlation between placental inflammation and clinical outcome. The results were as follows: (1) A higher rate of chorionitis and chorionic plate inflammation exist in patients with PROM. The inflammation rate of chorionic plate was 90% in patients with labor lasting longer than 12 hours, and only 38% in patients with a duration less than 12 hours. The difference was highly significant (P less than 0.01). (2) The positive rate of neonatal pharyngeal culture was higher in the PROM group than that in the control group (P less than 0.01). (3) Inflammation of chorionic plate was seen in 6/6 of the cases with neonatal infection. The corresponding rate was only 38% in cases without neonatal infection (P less than 0.01). It is suggested that in patients with PROM, efforts should be made to shorten the time of labor and the neonates should be watched for possible infections in the presence of inflammation of the placenta, particularly the chorionic plate.
对55例足月胎膜早破（PROM）孕妇和52例无胎膜早破的足月孕妇进行了母儿白细胞计数、新生儿咽拭子培养及胎盘组织学检查，以研究胎盘炎症与临床结局之间的相关性。结果如下：（1）胎膜早破患者绒毛膜羊膜炎和绒毛板炎的发生率较高。产程持续超过12小时的患者绒毛板炎症发生率为90%，而产程持续时间小于12小时的患者仅为38%。差异具有高度统计学意义（P<0.01）。（2）胎膜早破组新生儿咽拭子培养阳性率高于对照组（P<0.01）。（3）新生儿感染病例中6/6可见绒毛板炎症。无新生儿感染病例的相应发生率仅为38%（P<0.01）。提示对于胎膜早破患者，应努力缩短产程，且在胎盘存在炎症尤其是绒毛板炎症时，应密切观察新生儿是否可能发生感染。
