Lyell A, Bain W H, Thomson R M
Lancet. 1978 Sep 23;2(8091):657-9. doi: 10.1016/s0140-6736(78)92763-0.
Life-threatening peri-prosthetic incompetence developed with two successive nickel-containing mitral-valve prostheses in a patient allergic to nickel. Neither prosthesis had been incorporated satisfactorily. Her present nickel-free prosthesis seems to be satisfactory 22 months after insertion. Since allergy to nickel may have been involved in the failure of these prostheses, it is recommended that nickel-sensitive patients should be given nickel-free prostheses.
一名对镍过敏的患者在先后植入两枚含镍二尖瓣假体后出现危及生命的假体周围功能不全。两枚假体均未令人满意地整合。她目前植入的无镍假体在植入22个月后似乎状况良好。由于镍过敏可能与这些假体的失败有关，建议对镍敏感的患者使用无镍假体。
