Norozian-Amiri S M, Behnke J M
Department of Life Science, University of Nottingham.
Parasitology. 1994 Jul;109 ( Pt 1):119-28. doi: 10.1017/s0031182000077829.
Laboratory bred DSN hamsters were exposed to varying doses of infective larvae of Ancylostoma ceylanicum (orally) or Necator americanus (percutaneously) and were autopsied at times which corresponded to a period immediately before cessation of growth of worms or soon afterwards. A total of 829 (404 male and 425 female) A. ceylanicum and 1582 (781 male and 801 female) N. americanus were measured. At worm burdens of fewer than 100, the length of A. ceylanicum appeared to increase with infection intensity and no evidence was found that growth was retarded under crowded conditions. In an experiment comparing directly low (mean worm burden = 22) and heavy infections (mean worm burden = 180) significant negative associations between both weight and width, and worm burden were detected, but length again increased with worm burden. In contrast, 5 experiments with N. americanus indicated negative relationships between measures of worm size (length, width, wet and dry weight) and worm burden. It was concluded that N. americanus is subject to regulation by density-dependent processes within the host while A. ceylanicum is not sensitive to the same degree.
将实验室饲养的DSN仓鼠经口暴露于不同剂量的锡兰钩口线虫感染性幼虫，或经皮暴露于美洲板口线虫感染性幼虫，并在与蠕虫生长停止前或之后不久的时间段相对应的时间进行解剖。共测量了829条（404条雄性和425条雌性）锡兰钩口线虫和1582条（781条雄性和801条雌性）美洲板口线虫。在蠕虫负荷少于100条时，锡兰钩口线虫的长度似乎随感染强度增加，且未发现拥挤条件下生长受到抑制的证据。在一项直接比较低感染（平均蠕虫负荷 = 22条）和高感染（平均蠕虫负荷 = 180条）的实验中，检测到重量和宽度与蠕虫负荷之间均存在显著负相关，但长度再次随蠕虫负荷增加。相比之下，5项关于美洲板口线虫的实验表明，蠕虫大小测量值（长度、宽度、湿重和干重）与蠕虫负荷之间呈负相关。得出的结论是，美洲板口线虫在宿主体内受密度依赖过程的调节，而锡兰钩口线虫对该调节的敏感程度不同。
