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[儿童锥体外系疾病——关于病因发病机制和流行病学的临床问题]

[Extrapyramidal diseases in children--clinical problems regarding etiopathogenesis and epidemiology].

作者信息

Ignatowicz R, Michałowicz R, Ignatowiczowa L, Kmieć T

机构信息

Zespół Neurologii Dzieciecej, Warszawie.

出版信息

Postepy Hig Med Dosw. 1994;48(1):35-52.

PMID:8058579
Abstract

Clinical picture, etiopathogenesis and epidemiological analysis were performed on the extrapyramidal diseases of the children. Despite of advances in neurology and on the own observations etiopathogenesis of these syndromes remains unexplained. The abnormalities neurotransmitters of the brain is the main cause abnormal function of the basal ganglia. The various categories extrapyramidal syndromes are known, but a variety of intermediate forms have been described. The diagnosis extrapyramidal diseases in children despite recent advances in neurology and genetic remains very difficult.

摘要

对儿童锥体外系疾病进行了临床表现、病因发病机制及流行病学分析。尽管神经学有进展且基于自身观察,但这些综合征的病因发病机制仍未明确。脑内神经递质异常是基底神经节功能异常的主要原因。已知有各类锥体外系综合征,但也描述了多种中间形式。尽管神经学和遗传学方面近来有所进展,但儿童锥体外系疾病的诊断仍然非常困难。

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