Butugan O, Bogar P, Sennes L U, Ognibene R, Ishida L, da Silveira J A, Rosemberg S, Miniti A
ENT department, Hospital das clinicas de la FMUSP LIM-32, Sao Paulo, Brésil.
Rev Laryngol Otol Rhinol (Bord). 1993;114(5):359-63.
The present paper presents 5 cases of olfactory neuroblastoma (NO), showing the problems concerning the diagnosis and treatment. The olfactory neuroblastoma is a rare tumor that represents 1 to 5% of the malignant tumors of the nasal cavity. The wide range of the patient's age associated with variety clinical and histological findings, made the diagnosis often difficult.
neuroblastoma has a difficult diagnosis; the histologic diagnosis should always be complemented by the immunohistochemical investigation; surgical resection with adequate margins is the first treatment on resectable lesions.
本文介绍了5例嗅神经母细胞瘤(NO)病例,展示了诊断和治疗方面的问题。嗅神经母细胞瘤是一种罕见肿瘤,占鼻腔恶性肿瘤的1%至5%。患者年龄范围广,伴有多种临床和组织学表现,使得诊断常常困难。
嗅神经母细胞瘤诊断困难;组织学诊断应始终辅以免疫组化检查;对可切除病变,手术切除并保证足够切缘是首选治疗方法。