Raymond E, Walter S, Goldwasser F, Espie M, Cuvier C, Extra J M, Marty M
Service d'oncologie médicale, hôpital Saint-Louis, Paris, France.
Rev Med Interne. 1994 May;15(5):318-24. doi: 10.1016/s0248-8663(05)81437-7.
Malignant disease metastatic to the eye is a common entity afflicting hundred patients each year. Breast carcinoma is the most common carcinoma responsible for ocular metastases with an estimated range probably closer to 30% and prevalence of 11.000 women by year in United-States. Breast carcinoma is followed by lung cancer and adenocarcinoma of an unknown primary. The diagnosis should be suspected in patient with history of carcinoma and a decreased visual acuity or any other visual symptom. The most useful diagnostic techniques include direct ophthalmoscopy, ultrasonography, computed tomography and magnetic resonance imaging. The cornerstone of treatment of ocular metastases remains radiation therapy. The overall response rates of earlier diagnosis, according to measurement of visual acuity, may be ranged from 72 to 94%. Early diagnosis and treatment of those lesions are a primary concern to maximize the quality of life until death of patients with metastatic disease. We report four cases of women with breast cancer metastatic to the eye.
转移性至眼部的恶性疾病是一种常见病症,每年折磨着数百名患者。乳腺癌是导致眼部转移的最常见癌症,在美国,估计其比例可能接近30%,每年有11000名女性患病。其次是肺癌和原发灶不明的腺癌。对于有癌症病史且视力下降或出现任何其他视觉症状的患者,应怀疑有此诊断。最有用的诊断技术包括直接检眼镜检查、超声检查、计算机断层扫描和磁共振成像。眼部转移瘤治疗的基石仍然是放射治疗。根据视力测量,早期诊断的总体缓解率可能在72%至94%之间。对这些病变进行早期诊断和治疗是首要关注点,以便在转移性疾病患者死亡前最大限度地提高生活质量。我们报告了4例乳腺癌转移至眼部的女性病例。