Merrill C F, Kaufman D I, Dimitrov N V
Michigan State University, Department of Medicine, East Lansing 48824-1317.
Cancer. 1991 Aug 1;68(3):623-7. doi: 10.1002/1097-0142(19910801)68:3<623::aid-cncr2820680330>3.0.co;2-l.
Breast cancer metastatic to the eye is a common entity occurring in up to 30% of women with metastatic disease. The prevalence of this lesion is not appreciated because of the dominant clinical picture of metastases occurring in other organs. The diagnosis should be suspected in any women with a history of breast cancer and any visual symptoms, particularly metamorphopsia and scotomata. A thorough ophthalmologic evaluation, aided by ultrasonography, computed tomography, or magnetic resonance scanning, usually confirms the diagnosis. Early treatment with radiation therapy can alleviate symptoms and control local disease. The recognition and treatment of this disorder is important in maximizing the quality of life in patients with metastatic breast cancer, especially because newer treatment regimens prolong survival and thereby increase the chances for ocular metastasis.
转移性乳腺癌累及眼部是一种常见情况,在高达30%的转移性疾病女性患者中出现。由于其他器官转移的主要临床表现,这种病变的患病率未得到重视。任何有乳腺癌病史且有任何视觉症状,特别是视物变形和暗点的女性都应怀疑有此病。借助超声、计算机断层扫描或磁共振扫描进行全面的眼科评估,通常可确诊。早期放射治疗可缓解症状并控制局部疾病。认识和治疗这种疾病对于提高转移性乳腺癌患者的生活质量很重要,特别是因为新的治疗方案延长了生存期,从而增加了眼部转移的机会。