Ishida T, Dorfman H D, Steiner G C, Norman A
Department of Orthopaedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, New York, New York 10467-2490.
Skeletal Radiol. 1994 May;23(4):247-52. doi: 10.1007/BF02412356.
Five unusual cases of cystic angiomatosis of bone which presented with the radiologic appearance of osteoblastic lesions are reported. Three patients were female (ages 37, 41, and 65 years) and two were male (ages 24 and 66 years). Although cystic angiomatosis of bone usually produces widespread osteolytic lesions with a honeycombed appearance in the skeletal system, multiple osteoblastic lesions mimicking metastatic osteoblastic carcinoma are sometimes seen. This radiological presentation has not been well emphasized in previous reports. Histologically, in addition to the angiomatous lesions, both mature thickened lamellar bone trabeculae and immature trabeculae of woven bone were found. In one of our patients, increasing density of the osteoblastic lesions was noted over time. One previous study has suggested that the age of the lesions of cystic angiomatosis is related to radiographic density. It is important to recognize this uncommon variant of cystic angiomatosis and to include this entity among the radiologic differential diagnoses when multiple osteoblastic lesions are encountered.
报告了5例表现为成骨细胞性病变影像学表现的骨囊性血管瘤病罕见病例。3例患者为女性（年龄分别为37、41和65岁），2例为男性（年龄分别为24和66岁）。尽管骨囊性血管瘤病通常在骨骼系统中产生广泛的溶骨性病变，呈蜂窝状外观，但有时也可见到类似转移性成骨细胞癌的多个成骨细胞性病变。这种影像学表现在以往的报告中未得到充分强调。组织学上，除血管瘤性病变外，还发现了成熟增厚的板层骨小梁和未成熟的编织骨小梁。在我们的1例患者中，随着时间的推移，成骨细胞性病变的密度增加。此前一项研究表明，骨囊性血管瘤病病变的年龄与放射学密度有关。认识到这种不常见的骨囊性血管瘤病变体，并在遇到多个成骨细胞性病变时将该实体纳入放射学鉴别诊断中很重要。
