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[糖尿病昏迷。1931年至1973年间752例病例报告]

[Diabetic coma. A report of 752 cases between 1931 and 1973].

作者信息

Prachar H, Bruneder H, Nobis H, Korp W

出版信息

MMW Munch Med Wochenschr. 1975 Apr 18;117(16):661-8.

PMID:805925
Abstract

752 diabetic comata (150 non-ketoacidotic and 602 ketoacidotic) from the period between 1931 and 1973 were investigated with regard to type of coma, age, sex, blood sugar, body type, previous therapy, presence of infections and their location and lethality. The blood sugar rose from 521 mg percent in the period from 1931-1940 to 701 mg percent in the period from 1971-73, and age from 33.9 to 53.7 years. Patients without ketoacidosis had higher blood sugar and were older than those with ketoacidosis. Lethality was higher in women than in men. Mortality was higher with obesity (28.8 percent compared to 20.1 percent). 23.9 percent of them were "manifestation" comata of which 43.1 percent died. The lowest lethality was found in the 453 diabetics who had been treated with insulin (14.6 percent). Infections were demonstrable in 431 patients (57.3 percent). Of these, 30.1 percent died, of patients without infections 19.6 percent died. Mortality was 74.6 percent where infections were present in two or more organs.

摘要

对1931年至1973年间的752例糖尿病昏迷患者(150例非酮症酸中毒昏迷和602例酮症酸中毒昏迷)进行了调查,内容包括昏迷类型、年龄、性别、血糖、体型、既往治疗情况、是否存在感染及其部位和致死率。血糖从1931 - 1940年期间的521毫克%升至1971 - 1973年期间的701毫克%,年龄从33.9岁升至53.7岁。非酮症酸中毒患者的血糖更高,年龄也比酮症酸中毒患者大。女性的致死率高于男性。肥胖患者的死亡率更高(分别为28.8%和20.1%)。其中23.9%为“症状性”昏迷,其中43.1%死亡。在453例接受胰岛素治疗的糖尿病患者中致死率最低(14.6%)。431例患者(57.3%)可检测到感染。其中,有感染的患者30.1%死亡,无感染的患者19.6%死亡。两个或更多器官存在感染时死亡率为74.6%。

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