González Silva M, Bernal M D, Cabezón I
Servicio de Hematología, Hospital del S.A.S. de La Línea de la Concepción, Cádiz.
Sangre (Barc). 1994 Apr;39(2):99-103.
To assess the haematological values of a rural population of school children in the province of Cádiz and to estimate the incidence of iron deficiency amongst them.
The study was performed on 250 children of both sexes aged between 5 and 16 years. Informed consent was obtained from their parents in every case. White cell count, red cell count, haemoglobin, MCV, MCH, MCHC and RDW were assessed with a Coulter S Plus Jr automatic cell counter; serum iron was measured with a Ferrochem II analyser; turbidimetric measure of transferrin was performed with turbitimer, and ferritin was measured by microparticle enzymoimmunoassay. The normality criteria for children given by WHO were used as a reference.
Of the 250 samples, 245 were evaluable, corresponding to 138 boys (56.3%) and 107 girls (43.7%) and the findings were stratified according to age. The mean values attained in each group were similar to those reported in other Mediterranean countries, and their age distribution was parallel in both sexes until age 11, when haemoglobin and haematocrit increase in boys due to the erythropoietic stimulus exerted by androgens. Iron deficiency was found in 35 children (14.2%); of them, 17 (6.9%) had hypo-ferritinaemia, 13 (5.3%) had hyposideraemia and 5 (2%) had a combination of the two. Iron-lack anaemia was present in 2 cases (0.8%).
The group under study is a sample of the normal school-age population of the area. The detection of iron deficiency in children is important due to the influence of this precursor in the physical and intellectual development.
评估加的斯省农村学龄儿童的血液学指标，并估算他们中铁缺乏症的发生率。
对250名年龄在5至16岁之间的男女儿童进行了研究。在每种情况下均获得了其父母的知情同意。使用库尔特S Plus Jr自动血细胞计数器评估白细胞计数、红细胞计数、血红蛋白、平均红细胞体积、平均红细胞血红蛋白含量、平均红细胞血红蛋白浓度和红细胞分布宽度；使用Ferrochem II分析仪测量血清铁；使用比浊仪进行转铁蛋白的比浊测定，并通过微粒酶免疫测定法测量铁蛋白。以世界卫生组织给出的儿童正常标准作为参考。
在250个样本中，有245个可评估，对应138名男孩（56.3%）和107名女孩（43.7%），并根据年龄对结果进行了分层。每组获得的平均值与其他地中海国家报告的平均值相似，在11岁之前两性的年龄分布平行，11岁时由于雄激素产生的促红细胞生成刺激，男孩的血红蛋白和血细胞比容增加。35名儿童（14.2%）被发现缺铁；其中，17名（6.9%）患有低铁蛋白血症，13名（5.3%）患有低铁血症，5名（2%）同时患有这两种情况。2例（0.8%）存在缺铁性贫血。
所研究的群体是该地区正常学龄人口的一个样本。鉴于这种先兆因素对身体和智力发育的影响，检测儿童缺铁情况很重要。
