Mathews W C, Fullerton S C
Department of Medicine, University of California, San Diego.
Arch Pathol Lab Med. 1994 Aug;118(8):807-10.
Knowledge of Toxoplasma seroprevalence among human immunodeficiency virus-infected patients identifies candidates for potential prophylaxis and may influence management among patients who present with mass lesions of the central nervous system. Toxoplasma antibody seroprevalence among persons with human immunodeficiency virus infection varies widely. We utilized an administrative and laboratory database (including 1599 patients with human immunodeficiency virus infection who were receiving medical care at the University of California-San Diego Medical Center, between July 1, 1986, and March 31, 1990) to estimate Toxoplasma seroprevalence. Of the 1599 patients, 344 underwent serum assays for Toxoplasma antibodies. The tested group was similar to other members of the cohort in distributions of sex, race, citizenship, and age. The overall mean (+/- SE) Toxoplasma seroprevalence was 16% +/- 2%. Potential bias in this estimate because of testing indication, misclassification, or testing frequency was small.
了解人类免疫缺陷病毒感染患者中的弓形虫血清流行率，有助于确定潜在预防措施的适用对象，并可能影响患有中枢神经系统占位性病变患者的治疗管理。人类免疫缺陷病毒感染者中弓形虫抗体的血清流行率差异很大。我们利用一个管理和实验室数据库（包括1986年7月1日至1990年3月31日期间在加利福尼亚大学圣地亚哥分校医学中心接受治疗的1599例人类免疫缺陷病毒感染患者）来估计弓形虫血清流行率。在这1599例患者中，344例接受了弓形虫抗体的血清检测。受试组在性别、种族、国籍和年龄分布上与队列中的其他成员相似。总体平均（±标准误）弓形虫血清流行率为16%±2%。由于检测指征、错误分类或检测频率导致的该估计值的潜在偏差很小。
