Gulisano M, Pirino A, Montella A
Istituto di Anatomia umana normale Università di Sassari.
Boll Soc Ital Biol Sper. 1993 Nov;69(11):655-9.
Three patients, undergoing surgery for pharyngeal carcinoma, were studied after their informed consence in the aim of ascertaining: 1) whether the routinary hemithyroidectomy in case of surgical treatment of the cancer of pyriform sinus is justified by a real probability of neoplastic invasion of the gland, and 2) which pathway the neoplasia follows in the metastatic process. In each patient a small amount of methylene blue solution was injected in the pyriform sinus submucosa, just before starting the surgical operation, currently including hemithyroidectomy. The stain spreads to the superior portion of the thyroid lobe, and seems to follow the periarterial lymphatic vessels. Even if further researches are necessary, the obtained data seem to justify routinary thyroidectomy in course of surgical treatment of the hypopharyngeal cancer.
对三名接受咽癌手术的患者在获得其知情同意后进行了研究，目的是确定：1）在梨状窦癌手术治疗中常规进行半甲状腺切除术是否因腺体存在肿瘤侵袭的实际可能性而合理；2）肿瘤在转移过程中遵循何种途径。在每位患者开始包括半甲状腺切除术在内的外科手术前，在梨状窦黏膜下注射少量亚甲蓝溶液。染料扩散至甲状腺叶的上部，似乎沿着动脉周围淋巴管扩散。即使还需要进一步研究，但所获得的数据似乎证明在下咽癌手术治疗过程中进行常规甲状腺切除术是合理的。
