Hornsey S, Kutsutani Y, Field S B
Radiology. 1975 Jul;116(1):171-4. doi: 10.1148/116.1.171.
The relative biological effectiveness (RBE) for damage to mouse lung was measured for single doses and up to 30 fractions of 8 MV x rays and fast neutrons, relative to 250 kVp x rays. With 8 MV x rays the RBE was 0.87 and did not vary with dose per fraction between 150 and 1200 rad. With fast neutrons the RBE did not vary from 1.5 at 1200 rad of x rays, which is about 30% lower than that for skin, to 3.7 at 150 rad of x rays, which is about 10% less than that for skin. The implications for treatment of the lung with fast neutrons are discussed.
相对于250 kVp X射线，测量了单剂量以及高达30次分割的8 MV X射线和快中子对小鼠肺部损伤的相对生物效应（RBE）。对于8 MV X射线，RBE为0.87，且在150至1200拉德的分次剂量之间不随剂量变化。对于快中子，RBE在相当于1200拉德X射线剂量时为1.5（比皮肤的RBE低约30%）至相当于150拉德X射线剂量时为3.7（比皮肤的RBE低约10%）之间变化。文中讨论了快中子治疗肺部疾病的意义。
