Jenkins P J, Plowman P N
Department of Radiotherapy, St Bartholomew's Hospital, West Smithfield, London, UK.
Br J Radiol. 1994 Jul;67(799):651-3. doi: 10.1259/0007-1285-67-799-651.
Unilateral kidney irradiation, above renal tolerance, is occasionally necessary in the treatment of flank tumours in childhood. Renal atrophy follows. There is often a gradual increase in the function of the contralateral kidney to compensate for the radiation injury. The development of this compensatory response appears to be influenced by both age and any dose of radiation received. We report the cases of two children who received high dose unilateral kidney radiotherapy as part of the multimodality treatment of a flank tumour and consider the influences on compensatory hypertrophy of the contralateral kidney.
在儿童侧腹肿瘤的治疗中，有时需要对单侧肾脏进行超过肾脏耐受剂量的照射。随后会出现肾萎缩。对侧肾脏的功能通常会逐渐增强以代偿辐射损伤。这种代偿反应的发展似乎受年龄和所接受的任何辐射剂量的影响。我们报告了两名儿童的病例，他们接受了高剂量单侧肾脏放疗，作为侧腹肿瘤多模式治疗的一部分，并探讨了对侧肾脏代偿性肥大的影响因素。
