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使用电阻抗剖面法进行温度场估计。II. 实验系统描述与模型结果。

Temperature field estimation using electrical impedance profiling methods. II. Experimental system description and phantom results.

作者信息

Moskowitz M J, Paulsen K D, Ryan T P, Pang D

机构信息

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755.

出版信息

Int J Hyperthermia. 1994 Mar-Apr;10(2):229-45. doi: 10.3109/02656739409009345.

DOI:10.3109/02656739409009345
PMID:8064182
Abstract

An electrical impedance tomography system has been developed and tested for the purpose of thermal imaging. Since impedance changes with temperature, images of impedance subtracted from normothermic baselines will provide a map of temperature data. A system was designed to be operational at 10-50 kHz and to utilize 16 external electrodes around the periphery of a tissue-equivalent phantom encompassing the region of interest. These electrodes serve as current sources for the 5 mA constant-current inputs and are also used for reading differential voltages. Hyperthermia treatments for cancer require that internal thermometry probes be inserted into the tumour volume. Linear arrays of electrodes with thermometry tracks for micro-dimension thermometry serve this function, as well as providing localized voltage measurements in the region of interest. The embedded temperature sensors provide a quality assurance and calibration standard for the linear arrays in reconstruction of impedance profiles. Results of transient heating experiments with conductive and ultrasound heating are shown where image reconstruction is performed using a finite element model. Temperature predictions in these studies were accurate to better than 1 degree C on average when using information from surface electrodes combined with internal linear arrays. Maximum temperature errors, however, was found to be > 5 degrees C which suggests that further noise reduction during data acquisition and improvements in the reconstructions algorithms are needed.

摘要

为了进行热成像,已经开发并测试了一种电阻抗断层成像系统。由于阻抗随温度变化,从正常体温基线中减去阻抗的图像将提供温度数据图。设计了一个系统,使其在10 - 50 kHz频率下运行,并在围绕包含感兴趣区域的组织等效模型的周边使用16个外部电极。这些电极用作5 mA恒流输入的电流源,也用于读取差分电压。癌症的热疗需要将内部温度计探头插入肿瘤体积中。带有用于微尺寸温度测量的温度测量轨道的线性电极阵列具有此功能,同时还能在感兴趣区域提供局部电压测量。嵌入式温度传感器为阻抗分布重建中的线性阵列提供质量保证和校准标准。展示了使用导电加热和超声加热的瞬态加热实验结果,其中使用有限元模型进行图像重建。在这些研究中,当结合使用表面电极和内部线性阵列的信息时,温度预测平均精度优于1℃。然而,发现最大温度误差> 5℃,这表明在数据采集期间需要进一步降低噪声,并改进重建算法。

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