Lew D, Marino A A, Startzell J M, Keller J C
Department of Oral and Maxillofacial Surgery, University of Iowa, Iowa City 52242.
J Oral Maxillofac Surg. 1994 Sep;52(9):952-8; discussion 959. doi: 10.1016/s0278-2391(10)80078-3.
This study was undertaken to compare the relative rates and extent of osseointegration of dental implants when placed simultaneously with either corticocancellous block or particulate corticocancellous bone grafts.
Using the canine ilium as a model site, the implants were placed so that each served as its own control. The implants were harvested at 1, 2, or 3 months for evaluation by light microscopy, microradiography, and histomorphometry.
Both types of grafts were determined to be viable by microscopic evaluation of fluorescent labels. Qualitatively there appeared to be greater bone density in the corticocancellous block graft implant sites. At 3 months, the block graft implant sites had a level of osseointegration (59.6%) that approximated the control implant sites (65.2%), but was significantly greater than the particulate graft sites (39.2%).
These results indicate that implants in corticocancellous block grafts develop osseointegration more rapidly than those in particulate bone grafts. The clinical implications of these findings are discussed.
本研究旨在比较与皮质松质骨块状移植物或颗粒状皮质松质骨移植物同时植入时牙种植体的相对骨整合速率和程度。
以犬髂骨作为模型部位，植入种植体，使每个种植体自身作为对照。在1、2或3个月时取出种植体，通过光学显微镜、显微放射照相术和组织形态计量学进行评估。
通过对荧光标记的显微镜评估确定两种类型的移植物均存活。定性来看，皮质松质骨块状移植物植入部位的骨密度似乎更高。在3个月时，块状移植物植入部位的骨整合水平（59.6%）接近对照种植体部位（65.2%），但显著高于颗粒状移植物部位（39.2%）。
这些结果表明，皮质松质骨块状移植物中的种植体比颗粒状骨移植物中的种植体骨整合发展得更快。讨论了这些发现的临床意义。
