Grooters A M, Sherding R G, Biller D S, Johnson S E
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus.
J Vet Intern Med. 1994 May-Jun;8(3):203-6. doi: 10.1111/j.1939-1676.1994.tb03216.x.
Two diabetic dogs were presented for anorexia, persistent fever, and poor control of hyperglycemia. Both had neutrophilia with left shift, hypoalbuminemia, and increased serum alkaline phosphatase (SAP) activity. Radiography indicated intrahepatic gas densities in 1 dog and a hepatic mass in the other. Abdominal sonography demonstrated multiple well-demarcated hypoechoic hepatic lesions consistent with abscesses. Both dogs were successfully treated by surgical resection of the abscessed liver lobes in conjunction with antibiotics and supportive therapy. Good control of hyperglycemia was achieved in both dogs after recovery. Intracellular and extracellular Gram-negative rod-shaped bacteria were abundant in the abscesses from both dogs. These cases suggest an association between diabetes mellitus and hepatic abscessation.
两只患糖尿病的犬只因食欲不振、持续发热和高血糖控制不佳前来就诊。两只犬均有核左移的中性粒细胞增多、低白蛋白血症以及血清碱性磷酸酶（SAP）活性升高。放射检查显示，一只犬肝脏内有气体密度影，另一只犬肝脏内有肿块。腹部超声检查发现多个边界清晰的低回声肝脏病变，诊断为肝脓肿。两只犬均通过手术切除患脓肿的肝叶，并结合抗生素治疗和支持疗法成功治愈。康复后，两只犬的高血糖均得到良好控制。两只犬脓肿内均有大量细胞内和细胞外革兰氏阴性杆菌。这些病例表明糖尿病与肝脓肿之间存在关联。
