Abu-Shakra M, Nicol P, Urowitz M B
University of Toronto Rheumatic Disease Unit, Wellesley Hospital, ON, Canada.
J Rheumatol. 1994 May;21(5):934-7.
We describe a patient with seropositive erosive rheumatoid arthritis (RA) who developed accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate (MTX) therapy while her arthritis remained inactive. MTX is an effective therapy for the articular manifestations of RA. However, on occasion it may result in triggering the development of extraarticular manifestations of RA.
我们描述了一名血清学阳性的侵蚀性类风湿关节炎（RA）患者，该患者在甲氨蝶呤（MTX）治疗期间出现了结节病加速进展、胸腔积液和心包填塞，而其关节炎仍处于非活动状态。MTX是治疗RA关节表现的有效疗法。然而，偶尔它可能会导致RA关节外表现的发生。
