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[减压性颅骨切除术对药物治疗无法控制的颅内高压的临床疗效评估]

[Evaluation of the clinical benefit of decompression hemicraniectomy in intracranial hypertension not controlled by medical treatment].

作者信息

Jourdan C, Convert J, Mottolese C, Bachour E, Gharbi S, Artru F

机构信息

Service d'Anesthésie Réanimation, Hôpital Neurologique Pierre-Wertheimer, Lyon.

出版信息

Neurochirurgie. 1993;39(5):304-10.

PMID:8065488
Abstract

Through the findings in the literature on the basis of 9 personal cases, we review the indications and value of decompressive hemicraniectomy with plasty of the dura mater in cases of medically uncontrolled and decompensated intracranial hypertension. Seven patients had a pseudo-tumoral brain infarction. Five patients survived and their functional recovery is consistent with an autonomous daily life. Another patient with acute traumatic sub-dural haemorrhage died. The ninth patient had presuppurative encephalitis and recovered with no disability. At the time of surgery, all the patients were comatose with herniation of the mesencephalon (n = 3), uncal transtentorial herniation which was either unilateral (n = 4) or bilateral (n = 2). ICP was between 25 and 60 mmHg before the operation. After flap removal, ICP decreased by 15% and, after opening of the dura, it fell a further 70%. In 6 patients we were able to carry out continued post-operative monitoring of ICP, which stayed below 50% of initial values. Decompressive hemicraniectomy is an effective means of treating ICH caused by carotid cerebrovascular accidents with a high degree of edema, where mortality rises to 70-85% when only medical treatment is administered. No haemorrhagic complications, which can occur during hemispherectomies, were observed during decompression.

摘要

基于9例个人病例的文献研究结果,我们回顾了在药物治疗无法控制且失代偿性颅内高压的病例中,硬脑膜成形去骨瓣减压术的适应症和价值。7例患者患有假性肿瘤性脑梗死。5例患者存活,其功能恢复情况与能够自主进行日常生活一致。另1例急性创伤性硬膜下出血患者死亡。第9例患者患有化脓前期脑炎,康复后无残疾。手术时,所有患者均昏迷,伴有中脑疝(n = 3)、单侧(n = 4)或双侧(n = 2)钩回经天幕疝。术前颅内压在25至60 mmHg之间。去除骨瓣后,颅内压下降了15%,打开硬脑膜后,又进一步下降了70%。6例患者术后能够持续监测颅内压,其颅内压维持在初始值的50%以下。去骨瓣减压术是治疗由颈动脉脑血管意外导致的伴有高度水肿的脑出血的有效方法,仅采用药物治疗时死亡率会升至70 - 85%。减压过程中未观察到在大脑半球切除术中可能出现的出血并发症。

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