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[妊娠期肾积水。超声检查研究]

[Hydronephrosis in pregnancy. Ultrasonographic study].

作者信息

Croce P, Signorelli P, Chiapparini I, Dedè A

机构信息

Divisione di Ginecologia ed Ostetricia, Civico Ospedale di Codogno Milano.

出版信息

Minerva Ginecol. 1994 Apr;46(4):147-53.

PMID:8065586
Abstract

Hydronephrosis is a common pathology during pregnancy and according to some authors affects between 80 and 90% of women in the third trimester. The right side is most frequently affected. Moreover, there appears to be no relation between parity and hydronephrosis or between previous infections of the urinary tract and hydronephrosis; however its presence, especially if severe, is associated with urinary infections with a frequency which is significantly greater than in patients with a urinary tract within normal limits. There are two pathogenetic hypotheses: one identifies the inhibitory effect of progesterone and prostaglandins on muscular tone and the peristalsis of smooth ureteral muscle, with consequent dilatation and anfractuosity of the excretory tract above the pelvic brim; the other is the mechanical hypothesis based on the possible compression of the ureter caused by the pregnant womb at the level of the pelvic brim at the intersection with the ilial and ovarian vessels. One hypothesis does not exclude the other, but on the contrary they complement each other and give added plausibility to a multifactorial pathogenesis. The study of hydronephrosis in pregnancy has made considerable progress since the introduction of echotomography in image diagnosis, a low-cost method which is easy to use and does not harm the product of conception. Echographs with 3.5 MHz probes were used to carry out a prospective study by examining the kidneys and excretory tract in 370 asymptomatic pregnant women during the first, second and third trimesters of gestation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

肾积水是孕期常见的病理情况,据一些作者称,在孕晚期80%至90%的女性会受其影响。右侧最常受累。此外,胎次与肾积水之间、既往泌尿系统感染与肾积水之间似乎并无关联;然而,肾积水的存在,尤其是重度肾积水,与泌尿系统感染相关,其发生频率显著高于泌尿系统正常的患者。有两种发病机制假说:一种认为孕酮和前列腺素对输尿管平滑肌张力及蠕动有抑制作用,导致盆腔边缘以上排泄道扩张和迂曲;另一种是机械假说,基于妊娠子宫在盆腔边缘与髂血管和卵巢血管交汇处可能对输尿管造成压迫。一种假说并不排除另一种,相反,它们相互补充,使多因素发病机制更具合理性。自从超声断层扫描应用于影像诊断以来,孕期肾积水的研究取得了显著进展,超声断层扫描是一种低成本、易于使用且不会损害胎儿的方法。使用3.5兆赫探头的超声仪对370名无症状孕妇在妊娠早、中、晚期进行肾脏和排泄道检查,开展了一项前瞻性研究。(摘要截选于250字)

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