Kaufman E, Heling I, Rotstein I, Friedman S, Sion A, Moz C, Stabholtz A
Hospital Oral Medicine Service, Hebrew University, Hadassah School of Dental Medicine, Jerusalem, Israel.
Oral Surg Oral Med Oral Pathol. 1994 Jun;77(6):651-4. doi: 10.1016/0030-4220(94)90329-8.
The intraligamentary injection of a slow-release steroidal, the anti-inflammatory agent slow-release methylprednisolone (Depomedrol), was compared to a placebo and to an active placebo (Mepivacaine) in preventing postoperative pain after root canal treatment. The results clearly demonstrated that the tested drug significantly reduced the frequency and intensity of postoperative pain sequelae in the experimental set-up.
在根管治疗后预防术后疼痛方面，将缓释甾体抗炎药——缓释甲泼尼龙（德宝松）的韧带内注射与安慰剂及活性安慰剂（甲哌卡因）进行了比较。结果清楚地表明，在该实验设置中，受试药物显著降低了术后疼痛后遗症的频率和强度。
