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灵长类动物的实验性脊柱侧凸。一种技术的失败。

Experimental scoliosis in primates. Failure of a technique.

作者信息

Robin G C, Stein H

出版信息

J Bone Joint Surg Br. 1975 May;57(2):142-5.

PMID:806595
Abstract

An attempt to produce scoliosis in young baboons by excision of the heads of ribs failed in thirteen growing animals observed for up to a year after operation. Other investigators have failed to produce scoliosis in primates by similar and other techniques that had successfully produced scoliosis in quadruped animals. The possible reasons for this are discussed, especially in the light of clinical trials that are being carried out with techniques transposed from the quadruped experimental animal to the scoliosis clinic.

摘要

通过切除肋骨头部在幼年狒狒中诱发脊柱侧凸的尝试,在术后观察长达一年的13只生长中的动物身上均告失败。其他研究者也未能通过类似的以及其他曾在四足动物中成功诱发脊柱侧凸的技术,在灵长类动物中诱发脊柱侧凸。本文讨论了其中可能的原因,尤其是鉴于正在开展的临床试验,这些试验采用的技术是从四足实验动物移植到脊柱侧凸临床治疗中的。

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