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[恒河猴感染猴免疫缺陷病毒(SIV)所致感染的免疫表现及细胞学特征]

[The immunological manifestations and cytological characteristics of infection caused by the simian immunodeficiency virus (SIV) in rhesus monkeys].

作者信息

Persidskiĭ Iu V, Shcherbinskaia A M, Barshteĭn Iu A, Antonenko S V, Marichev I L

出版信息

Tsitol Genet. 1993 Nov-Dec;27(6):97-104.

PMID:8066812
Abstract

The results of immunological and morphological studies of Asian macaques (Macaca mulatta) infected by simian immunodeficiency virus (SIV) are summarized in this review of literature. This virus causes development of the immunodeficiency disease that closely resembles human AIDS. Immunological parameters (CD count, antibody response etc.) are described promoting prediction of progression of immunodeficiency in monkeys. The morphological features of injury of internal organs indicate that SIV-induced immunodeficiency is the multisystem disease.

摘要

本文献综述总结了感染猿猴免疫缺陷病毒(SIV)的亚洲猕猴(恒河猴)的免疫学和形态学研究结果。这种病毒会引发与人类艾滋病极为相似的免疫缺陷疾病。文中描述了免疫参数(CD计数、抗体反应等),有助于预测猴子免疫缺陷的进展情况。内脏损伤的形态学特征表明,SIV诱导的免疫缺陷是一种多系统疾病。

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