Borodaĭ N V, Ganina K P, Glushchenko N N
Tsitol Genet. 1994 Jan-Feb;28(1):73-6.
Patients with malignant melanomas and breast cancer (83 men and women) were examined. On the basis of study of the DNA contents in nuclei of epitheliocytes from the mucous oral cavity, index of their nuclei heterogeneity we have revealed disturbances in maturation and differentiation of cells. They were arranged to the spinous layer of the oral mucosa. The disturbances were caused by the tumour influence on the functional state of the mucosa.
对患有恶性黑色素瘤和乳腺癌的患者（83名男性和女性）进行了检查。基于对口腔黏膜上皮细胞核中DNA含量及其核异质性指数的研究，我们发现细胞成熟和分化存在紊乱。这些细胞排列在口腔黏膜的棘层。这些紊乱是由肿瘤对黏膜功能状态的影响所致。
