[生物胺在红细胞鉴别诊断中的作用]
[Biogenic amines in the differential diagnosis of erythrocytes].
作者信息
Gaĭdukova S N, Tishchenko L M, Vydyborets S V
出版信息
Lik Sprava. 1994 Jan(1):50-2.
Free histamine (FH) and free serotonin (FS) were studied fluorometrically in blood serum of 26 patients with genuine polycythemia (GP), 52 patients with chronic obstructive bronchitis (COB) associated with secondary erythrocytosis (SE) and 29 healthy subjects. On the grounds of the results of the study criteria of GP and COB-related SE were suggested. Diagnosis of GP can be considered valid if content of FH is no more than 3.1 times, FS content no less than 3 times and FH/FS ratio is no more than 2.65 times as much as normal. Levels of FH and FS and FH/FS ratio in SE related to COB are characterized by 4-fold and more, 2.9 and less and 4.64 and more increase respectively.
采用荧光法对26例真性红细胞增多症（GP）患者、52例伴有继发性红细胞增多症（SE）的慢性阻塞性支气管炎（COB）患者以及29名健康受试者的血清中的游离组胺（FH）和游离血清素（FS）进行了研究。基于研究结果，提出了GP和COB相关SE的诊断标准。如果FH含量不超过正常的3.1倍、FS含量不少于正常的3倍且FH/FS比值不超过正常的2.65倍，则GP的诊断可被认为有效。与COB相关的SE中的FH和FS水平以及FH/FS比值分别以增加4倍及以上、2.9及以下和4.64及以上为特征。
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