Knoll P, Bonatti G, Pitscheider W, Psenner K, Erlicher A, Zammarchi A, Crepaz R
Abteilung für Kardiologie, Allgemeines Regionalkrankenhaus Bozen.
Z Kardiol. 1994 Jun;83(6):439-45.
Patients with previous coronary artery bypass graft surgery often present with pain of unknown origin. Noninvasive documentation of graft patency is of obvious clinical importance.
In order to assess the efficacy of magnetic resonance imaging (MRI) in evaluating graft patency, 44 patient with prior coronary artery bypass graft surgery and a history of chest pain were studied by coronarography and MRI. MRI was performed within 2.1 +/- 3.8 days from coronarography using a 0.5 Tesla magnet, Spin-Echo T1 technique, cardiac and respiratory gating and scannings in transaxial plans. A graft was defined as patent, if a signal void was identified in at least two different slices in a position consistent with a bypass graft. Images were analyzed by two different observers aware of the type of surgery but not the result of the coronarography.
Eighty-nine out of 100 grafts were classified correctly by MRI. Sixty-three grafts were patent as shown by coronarography; 59 of them were classified correctly by MRI. Thirty-seven grafts were shown as occluded; 30 of them were classified correctly by MRI. In particular, 43 out of 45 grafts to the left anterior descending artery, 18 of them using the internal mammary artery, 23 out of 30 graft to the left circumflex artery and 23 out 25 grafts to the right coronary artery were classified correctly.
This study demonstrates the capability of MRI to evaluate coronary artery bypass graft patency with a sensitivity of 94% and specificity of 81%; this technique has significantly clinical limitations because resolution is not adequate to evaluate the presence of graft stenosis.
曾接受冠状动脉旁路移植手术的患者常出现不明原因的疼痛。无创记录移植血管通畅情况具有明显的临床重要性。
为评估磁共振成像(MRI)在评估移植血管通畅性方面的疗效,对44例曾接受冠状动脉旁路移植手术且有胸痛病史的患者进行了冠状动脉造影和MRI检查。在冠状动脉造影后2.1±3.8天内,使用0.5特斯拉磁体、自旋回波T1技术、心脏和呼吸门控,并在横轴位进行扫描,完成MRI检查。如果在与旁路移植血管位置一致的至少两个不同层面中识别出信号缺失,则将移植血管定义为通畅。由两名知晓手术类型但不知冠状动脉造影结果的观察者对图像进行分析。
MRI正确分类了100条移植血管中的89条。冠状动脉造影显示63条移植血管通畅;其中59条被MRI正确分类。37条移植血管显示为闭塞;其中30条被MRI正确分类。特别是,45条左前降支移植血管中的43条、其中18条使用乳内动脉,30条左旋支移植血管中的23条以及25条右冠状动脉移植血管中的23条被正确分类。
本研究表明MRI评估冠状动脉旁路移植血管通畅性的能力,敏感性为94%,特异性为81%;由于分辨率不足以评估移植血管狭窄的存在,该技术存在明显的临床局限性。