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体外兆伏级放射治疗根治性前列腺切除术后残留或复发性肿瘤的初步结果

External-bean megavoltage radiation therapy in the treatment of post-radical prostatectomy residual or recurrent tumor preliminary results.

作者信息

Ray G R, Cassady J R, Bagshaw M A

出版信息

J Urol. 1975 Jul;114(1):98-101. doi: 10.1016/s0022-5347(17)66953-2.

DOI:10.1016/s0022-5347(17)66953-2
PMID:806707
Abstract

High dose, external-beam megavoltage radiation therapy was administered to 21 patients because of incomplete excision (11 patients) or palpable local recurrence (10 patients) following radical prostatectomy. Of the 21 patients 8 were alive without clinical evidence of cancer for 29 to 97 months after radiation therapy. The best survival was in the 11 patients referred because of incomplete excision. Of these 11 patients 9 were alive, 6 without cancer, and 2 were dead of intercurrent disease without evidence of cancer. Of the 10 patients with palpable local recurrence 2 were alive without evidence neoplasm, while 2 died of intercurrent disease without cancer. Acute treatment-associated symptoms occurred in 11 of the 21 patients. Generally, these symptoms were mild and responded to conservative, symptomatic management. Two serious complications were recorded.

摘要

21例患者因前列腺癌根治术后切除不完全(11例)或可触及局部复发(10例)接受了大剂量体外兆伏级放射治疗。21例患者中,8例在放疗后29至97个月存活且无癌症临床证据。因切除不完全转诊的11例患者生存情况最佳。这11例患者中,9例存活,6例无癌症,2例死于并发疾病,无癌症证据。10例可触及局部复发的患者中,2例存活且无肿瘤证据,2例死于并发疾病,无癌症。21例患者中有11例出现了与治疗相关的急性症状。一般来说,这些症状较轻,采用保守的对症治疗有效。记录到两例严重并发症。

相似文献

1
External-bean megavoltage radiation therapy in the treatment of post-radical prostatectomy residual or recurrent tumor preliminary results.体外兆伏级放射治疗根治性前列腺切除术后残留或复发性肿瘤的初步结果
J Urol. 1975 Jul;114(1):98-101. doi: 10.1016/s0022-5347(17)66953-2.
2
External beam radiation salvage for residual or recurrent local tumor following radical prostatectomy.根治性前列腺切除术后对残留或复发性局部肿瘤进行体外束放射挽救治疗。
J Urol. 1984 Nov;132(5):926-30. doi: 10.1016/s0022-5347(17)49951-4.
3
Radiotherapy of local recurrence following radical prostatectomy.
Strahlenther Onkol. 1992 Jun;168(6):333-6.
4
Salvage radiotherapy for men with isolated rising PSA or locally palpable recurrence after radical prostatectomy: do outcomes differ?前列腺癌根治术后孤立性PSA升高或局部可触及复发男性患者的挽救性放疗:结局是否不同?
Urology. 2004 Oct;64(4):760-4. doi: 10.1016/j.urology.2004.05.016.
5
Re: External beam radiation salvage for residual or recurrent local tumor following radical prostatectomy.
J Urol. 1985 Nov;134(5):975-6. doi: 10.1016/s0022-5347(17)47562-8.
6
Adjuvant radiotherapy following radical prostatectomy: results and complications.
J Urol. 1986 Jan;135(1):65-8. doi: 10.1016/s0022-5347(17)45519-4.
7
Prostatic carcinoma: complications of megavoltage radiation therapy.前列腺癌:兆伏级放射治疗的并发症
Br J Urol. 1986 Feb;58(1):52-4. doi: 10.1111/j.1464-410x.1986.tb05427.x.
8
Definitive radiotherapy following prostatectomy: results and complications.前列腺切除术后的确定性放疗:结果与并发症
Int J Radiat Oncol Biol Phys. 1986 Feb;12(2):185-9. doi: 10.1016/0360-3016(86)90092-1.
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J Urol. 1998 Nov;160(5):1748-53.
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[Survival after radical retropubic prostatectomy in patients with poorly differentiated prostatic carcinoma].
Strahlenther Onkol. 1996 Jul;172(7):404-5.