Ray G R, Cassady J R, Bagshaw M A
J Urol. 1975 Jul;114(1):98-101. doi: 10.1016/s0022-5347(17)66953-2.
High dose, external-beam megavoltage radiation therapy was administered to 21 patients because of incomplete excision (11 patients) or palpable local recurrence (10 patients) following radical prostatectomy. Of the 21 patients 8 were alive without clinical evidence of cancer for 29 to 97 months after radiation therapy. The best survival was in the 11 patients referred because of incomplete excision. Of these 11 patients 9 were alive, 6 without cancer, and 2 were dead of intercurrent disease without evidence of cancer. Of the 10 patients with palpable local recurrence 2 were alive without evidence neoplasm, while 2 died of intercurrent disease without cancer. Acute treatment-associated symptoms occurred in 11 of the 21 patients. Generally, these symptoms were mild and responded to conservative, symptomatic management. Two serious complications were recorded.
21例患者因前列腺癌根治术后切除不完全(11例)或可触及局部复发(10例)接受了大剂量体外兆伏级放射治疗。21例患者中,8例在放疗后29至97个月存活且无癌症临床证据。因切除不完全转诊的11例患者生存情况最佳。这11例患者中,9例存活,6例无癌症,2例死于并发疾病,无癌症证据。10例可触及局部复发的患者中,2例存活且无肿瘤证据,2例死于并发疾病,无癌症。21例患者中有11例出现了与治疗相关的急性症状。一般来说,这些症状较轻,采用保守的对症治疗有效。记录到两例严重并发症。